NU 2058

Catalogue number: N925240
Chemical name: NU 2058
Synonyms: 6-(Cyclohexylmethoxy)-9H-purin-2-amine; 6-(Cyclohexylmethoxy)-1H-purin-2-amine; 2-Amino-6-(cyclohexylmethoxy)purine; O6-(Cyclohexylmethyl)guanine; 6-(Cyclohexylmethoxy)-7H-purin-2-amine
CAS Number: 161058-83-9
Possible CAS #: NA
Molecular form.: C₁₂H₁₇N₅O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 247.3
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: NU 2058 is an intermediate of NU 6140 (N925295), a cyclin-dependant kinase 2 inhibitor which demonstrates 10-36 fold selectivity against Cdk2-cyclin A. This selectivity induces cell-cycle arrest at the G2-M phase and potentiates the apoptotic effect of pacitaxel.
Dangerous Goods Info: NA
References: Pennati, M. et al.: Mol. Canc. Ther., 4, 1328 (2005)
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $50.00
10mg $140.00
50mg $575.00
  Pack size Price(USD)
5mg $85.00
25mg $300.00
100mg $950.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Available in 2-3 weeks

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