Catalogue number: N900300
Chemical name: NSC-33994
Synonyms: 4,4’-[(1E)-1,2-Diethyl-1,2-ethenediyl]bis[2-[(diethylamino)methyl]phenol; (E)-4,4’-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol;
CAS Number: 82058-16-0
Possible CAS #: NA
Molecular form.: C₂₈H₄₂N₂O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 438.65
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: NSC-33994 is novel inhibitor of JAK2 tyrosine kinase (Janus kinase 2 ). Janus kinase 2 (JAK2) plays a crucial role in the pathomechanism of myeloproliferative disorders and hematological malignancies.
Dangerous Goods Info: NA
References: Tanner, J., et al.: J. Biol. Chem., 270, 6523 (1995), Rane, S., et al.: Oncogene, 19, 5662 (2000, Verma, A., et al.: Cancer Metastasis Rev., 22, 423 (2003), Levine, R., et al.: Cancer Cell., 7, 387 (2005), Kiss, et al.: Bioorg. Med. Chem. Lett., 19, 3598 (2009),
Peer Review Product Citations:

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