NS 3623

Catalogue number: N900250
Chemical name: NS 3623
Synonyms: 1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea; N-[4-Bromo-2-(2H-tetrazol-5-yl)phenyl]-N’-[3-(trifluoromethyl)phenyl]-urea
CAS Number: 343630-41-1
Possible CAS #: NA
Molecular form.: C₁₅H₁₀BrF₃N₆O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 427.18
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Agonist, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: NS 3623 selectively activates the human ether-a-go-go related gene (hERG) potassium channel which mediates the repolarizing cardiac current IKr. NS 3623 an IKr agonist, cause QT interval prolongation, increasing the risk of dangerous ventricular fibrillations, eventually leading to sudden cardiac death.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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