Nitrocefin (>90%)

Catalogue number: N493815
Chemical name: Nitrocefin (>90%)
Synonyms: (6R,7R)-3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; [6R-[3(E),6α,7β]]-3-[2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;
CAS Number: 41906-86-9
Possible CAS #: NA
Molecular form.: C₂₁H₁₆N₄O₈S₂
Appearance: Red-Orange Solid
Melting Point: >99°C (dec.)
Mol. Weight: 516.5
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO, Methanol
Stability: Unstable in Solution
Category: Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Metabolites & Impurities, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: Nitrocefin is a chromogenic β-lactamase substrate that undergoes colour change from yellow to red as the amide bond in the β-Lactam ring is hydrolyzed by β-lactamase. Nitrocefin undergoes colour changes induced by lactamases produced by Gram-positive and Gram-negative bacteria. Several studies have utilized the colour changing properties of Nitrocefin for the detection of β-lactamase activity from bacterial cell extracts by isoelectric focusing and spectroscopy. Nitrocefin has also been used in studies involving β-lactamase resistant antibiotics.
Dangerous Goods Info: NA
References: Yang, H., et al.: Biochem., 51, 3839 (2012); El, Z., et al.: J. Pure. Applied. Microbiol, 5, 511 (2011); Nguyen, H.M., et al.: J. Chem. Info. Modeling., 51, 3226 (2011);
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $45.00
10mg $125.00
50mg $425.00
  Pack size Price(USD)
5mg $70.00
25mg $280.00
100mg $725.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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