1,4-O-Didesmethyl rac-Niranthin-d4

Catalogue number: N480992
Chemical name: 1,4-O-Didesmethyl rac-Niranthin-d4
Synonyms: (2R,3R)-rel-2-[(3,4-dimethoxyphenyl)methyl]-3-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-1,4-butanediol-d4; (R*,R*)-2-[(3,4-Dimethoxyphenyl)methyl]-3-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-1,4-butanediol-d4; (R*,R*)-(±)-2-[(3,4-Dimethoxyphenyl)methyl]-3-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-1,4-butanediol-d4;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₂H₂₄D₄O₇
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 408.48
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Labelled 1,4-O-Didesmethyl rac-Niranthin is an intermediate in the synthesis of rac-Niranthin (N481000), a lignan compound isolated from the plant Phyllanthus amarus and shows anti-leishmanial activity. It acts through induction of topoisomerase I-mediated DNA-protein adduct formation in Leishmania cells triggering apoptosis of cellular nucleases. It also maintains the ability to reduce uric acid concentrations through xanthine oxidase inhibition.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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