β-Nicotinamide-d4 Mononucleotide (d3-major)

Catalogue number: N407768
Chemical name: β-Nicotinamide-d4 Mononucleotide (d3-major)
Synonyms: 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium-d4 Inner Salt; 3-Carbamoyl-1-β-D-ribofuranosylpyridinium-d4 Hydroxide, 5’-Phosphate Inner Salt; NMN; Nicotinamide-d4 Mononucleotide; Nicotinamide-d4 Ribonucleoside 5’-Phosphate; Nicotinamide-d4 Ribonucleotide; Nicotinamide-d4 Ribotide; β-D-NMN; β-NMN;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₁₁H₁₁D₄N₂O₈P
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 338.24
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Isotope Labelled Compounds, Nicotine Derivatives, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: β-Nicotinamide-d4 Mononucleotide is the labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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