β-Nicotinamide Mononucleotide

Catalogue number: N407765
Chemical name: β-Nicotinamide Mononucleotide
Synonyms: 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium Inner Salt; 3-Carbamoyl-1-β-D-ribofuranosylpyridinium Hydroxide, 5’-Phosphate Inner Salt; NMN; Nicotinamide Mononucleotide; Nicotinamide Ribonucleoside 5’-Phosphate; Nicotinamide Ribonucleotide; Nicotinamide Ribotide; β-D-NMN; β-NMN;
CAS Number: 1094-61-7
Possible CAS #: NA
Molecular form.: C₁₁H₁₅N₂O₈P
Appearance: White to Off-White Solid
Melting Point: >108°C (dec.)
Mol. Weight: 334.22
Storage: Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
Solubility: Methanol, Water
Stability: Very Hygroscopic
Category: Amines, Aromatics, Nicotine Derivatives, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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