trans-Ned-19

Catalogue number: N388750
Chemical name: trans-Ned-19
Synonyms: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;
CAS Number: 1354235-96-3
Possible CAS #: NA
Molecular form.: C₃₀H₃₁FN₄O₃
Appearance: Yellow Solid
Melting Point: 168-173°C
Mol. Weight: 514.59
Storage: Refrigerator
Solubility: Methanol
Stability: No Data Available
Category: Aromatics, Heterocycles, Indole Derivatives, Inhibitors, Fluorescent Labels & Indicators, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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Inventory Status:   In Stock

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