(-)-α-Narcotinediol

Catalogue number: N378890
Chemical name: (-)-α-Narcotinediol
Synonyms: [S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1,2-benzenedimethanol; α-Narcotinediol (8CI); 1,3-Dioxolo[4,5-g]isoquinoline, 1,2-benzenedimethanol deriv.; (-)-Narcotinediol; NSC 132826; NSC 279531; Narcotinediol
CAS Number: 23942-99-6
Possible CAS #: NA
Molecular form.: C₂₂H₂₇NO₇
Appearance: White Solid
Melting Point: No Data Available
Mol. Weight: 417.45
Storage: Refrigerator, under inert atmosphere
Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (-)-α-Narcotinediol is a Narcotine derivative, a noscapinoid class of microtubule binding compounds that alter microtubule dynamics without affecting tubulin polymer mass. Noscapinoids show great promise as chemotherapeutic agents for the treatment of human cancers. Unlike Narcotine, (-)-α-Narcotinediol deos not inhibit small-intestinal transport in rats.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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Inventory Status:   Pending QC

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