N-2-Naphthalenyl-glycine 2-[(3,5-Dibromo-2,4-dihydroxyphenyl)methylene]hydrazide

Catalogue number: N368340
Chemical name: N-2-Naphthalenyl-glycine 2-[(3,5-Dibromo-2,4-dihydroxyphenyl)methylene]hydrazide
Synonyms: GlyH 101
CAS Number: 328541-79-3
Possible CAS #: NA
Molecular form.: C₁₉H₁₅Br₂N₃O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 493.15
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: N-2-Naphthalenyl-glycine 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide is a glycine hydrazide that has recently been shown to block CFTR channels. However, its effects on cardiomyocytes are unknown. Studies have demonstrated that GlyH-101 blocks cardiac I Cl.PKA channels in a similar fashion to that reported for recombinant CFTR.
References: Barman, P.P., et al.: Biochem. Biophys. Res. Comm., 408, 12 (2011); Stahi, M., et al.: Am. J. Phys., 302, C67 (2012);
Dangerous Goods Info: NA

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