ML 3403

Catalogue number: M425090
Chemical name: ML 3403
Synonyms: 4-[5-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl]-N-(1-phenylethyl)-2-pyridinamine;
CAS Number: 549505-65-9
Possible CAS #: NA
Molecular form.: C₂₃H₂₁FN₄S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 404.5
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Boiling Point: No Data Available
Applications: ML 3403 is a potent and selective p38 mitogen-activated protein kinase (MAPK) inhibitor. MAPK is a key mediator in cytokine-induced signaling events and plays an integral role in disease states including oncogenesis, autoimmune diseases, and inflammatory processes. Therefore, MAPK inhibitors such as ML 3403 provides an attractive strategy for therapeutic intervention.
Dangerous Goods Info: NA
References: Kammerer, B. et al.: Xenobiotica, 37, 280 (2007); Kammerer, B. et al.: Drug Metab. Dispos., 35, 875 (2007); Gelmedin, V. et al.: Biochem. Pharmacol., 76, 1068 (2008);
Peer Review Product Citations:

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  Pack size Price(USD)
10mg $140.00
  Pack size Price(USD)
100mg $1120.00
Exact Weight Packaging ($75(USD) / Vial)
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