MK-2206 Dihydrochloride

Catalogue number: M425025
Chemical name: MK-2206 Dihydrochloride
Synonyms: 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Hydrochloride;
CAS Number: 1032350-13-2
Possible CAS #: NA
Molecular form.: C₂₅H₂₃Cl₂N₅O
Appearance: Yellow Solid
Melting Point: >255°C (dec.)
Mol. Weight: 480.39
Storage: Refrigerator
Solubility: Methanol, Water
Stability: No Data Available
Category: Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: AZD 6244 and MK 2206 are targeted small-molecule drugs that inhibit MEK and AKT responses. The combination of AZD6244 and MK2206 has a significant synergistic effect on tumor growth in vitro and in vivo and leads to increased survival rates in mice bearing highly aggressive human lung tumors. Antitumor agents.
Dangerous Goods Info: NA
References: Yeh, T., et al.: Clin. Cancer Res., 13, 1576 (2007), Meng, J., et al.: Cancer Biol. Ther., 8, 2073 (2009),
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $45.00
10mg $150.00
50mg $555.00
  Pack size Price(USD)
5mg $95.00
25mg $325.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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