Mevastatin Hydroxy Acid Sodium Salt

Catalogue number: M340510
Chemical name: Mevastatin Hydroxy Acid Sodium Salt
Synonyms: (βR,δR,1S,2S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt; [1S-[1α(βS*,δS*),2α,8β(R*),8aα]]-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid Monosodium Salt; (βR,δR,1S,2S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Monosodium Salt; ML 236B Sodium Salt;
CAS Number: 99782-89-5
Possible CAS #: NA
Molecular form.: C₂₃H₃₅NaO₆
Appearance: Off-White Solid
Melting Point: 142-145°C
Mol. Weight: 430.51
Storage: -20˚C Freezer
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: An active carboxylate of Mevastatin (M340500). It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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