Catalogue number: M331390
Chemical name: N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide
Synonyms: Deschloro Sorafenib; Sorafenib Impurity 3
CAS Number: 1285533-84-7
Possible CAS #: NA
Molecular form.: C₂₁H₁₇F₃N₄O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 430.38
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.
Dangerous Goods Info: NA
References: Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)
Peer Review Product Citations:

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