Isotope labelled 2-Methylthio-N6-isopentenyladenosine is located at position 37 in tRNAs that read codons starting with uridine. 2-Methylthio-N6-isopentenyladenosine in trpT(Su9) suppressor tRNA increase the efficiency of the tRNA by protecting it from ribosomal proofreading which is induced by codon context.
Dangerous Goods Info:
Diaz, I., Ehrenberg, M.: J. Mol. Biol., 222, 1161 (1991); Bjornsson, A., Isaksson, L.A.: J. Mol. Bio., 232, 1017 (1993)