trans-N-Methylphenyl Sertraline

Catalogue number: M327095
Chemical name: trans-N-Methylphenyl Sertraline
Synonyms: (1S,4R)-N-Benzyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine; (1S,4R)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-(phenylmethyl)-1-naphthalenamine
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₃H₂₁Cl₂N
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 382.33
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: trans-N-Methylphenyl Sertraline is a stereoisomer of rac-cis-N-Methylphenyl Sertraline (M327085), an intermediate in the synthesis of rac-cis-N-Desmethyl Sertraline Hydrochloride (D292100), a racemate of a metabolite of Sertraline. N-Desmethyl sertraline is significantly less active analogue as compared to the methylated compound, Sertraline.
Dangerous Goods Info: NA
References: Welch, W.M., et al.: J. Med. Chem., 27, 1508 (1984)
Peer Review Product Citations:

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