Catalogue number: M321252
Chemical name: Metanicotine-d3
Synonyms: (E)-N-[Methyl]-4-(3-pyridinyl)-3-buten-1-amine-d;, RJR 2403-d3; Rivanicline-d3; (E)-Metanicotine-d3
CAS Number: 220088-40-4
Possible CAS #: Unlabelled: 15585-43-0
Molecular form.: C₁₀H₁₁D₃N₂
Appearance: Clear Colourless Oil
Melting Point: N/A
Mol. Weight: 165.25
Storage: Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: No Data Available
Boiling Point: 99-101°C/0.4mm Hg
Applications: Metanicotine-d3 is the isotope labelled analog of Metanicotine (M321250); an alkaloid found in the leaves of Duboisia Hopwoodii and a constitutent of tobacco smoke. Also used as a potential drug for the treatment of senile dementia of the Alzheimer’s type, and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Schmeltz, I., et al.: J. Sci. Food Agric., 15, 744 (1964); Griffin, W.J. and Luanratana, O.: Phytochemistry, 21, 499 (1982); Jacob III, P., et al.: J. Chromatogr., 619, 49 (1993); Lippiello, P.M., et al.: J. Pharm. Exp. Therap., 279, 1422 (1996)
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $150.00
  Pack size Price(USD)
10mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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