α-Methyl-γ-hydroxy-1,N2-propano-2’-deoxyguanosine (Mixture of Diastereomers)

Catalogue number: M312890
Chemical name: α-Methyl-γ-hydroxy-1,N2-propano-2’-deoxyguanosine (Mixture of Diastereomers)
Synonyms: 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-4,6,7,8-tetrahydro-8-hydroxy-6-methylpyrimido[1,2-a]purin-10(3H)-one; α-Me-γ-OH-PdG; Cr-PdG;
CAS Number: 132014-87-0
Possible CAS #: NA
Molecular form.: C₁₄H₁₉N₅O₅
Appearance: White to Pale Yellow Solid
Melting Point: 135-137°C
Mol. Weight: 337.33
Storage: Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
Solubility: Methanol (Slightly), Water (Slightly)
Stability: No Data Available
Category: Carbohydrates & Derivatives, Heterocycles, Mutagenesis Research Chemicals
Boiling Point: No Data Available
Applications: A genotoxic cyclic adduct of 2’-deoxyguanosine with crotonaldehyde. Histones accelerate the cyclic 1,N2-propanoguanine adduct-formation of DNA by the primary metabolite of alcohol and carcinogenic crotonaldehyde.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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