Methyl (S)-(+)-3-Hydroxy-2-methylpropionate

Catalogue number: M312775
Chemical name: Methyl (S)-(+)-3-Hydroxy-2-methylpropionate
Synonyms: (+)-Methyl β-Hydroxyisobutyrate; (2S)-3-Hydroxy-2-methylpropanoic Acid Methyl Ester; (2S)-3-Hydroxy-2-methylpropionic Acid Methyl Ester; (S)-(+)-Roche Ester; (S)-2-Methyl-3-hydroxypropionic Acid Methyl Ester; (S)-3-Hydroxy-2-methylpropanoic Acid Methyl Ester; (S)-3-Hydroxy-2-methylpropionic Acid Methyl Ester; (S)-Roche Ester; Methyl (2S)-2-Hydroxymethylpropanoate; Methyl (2S)-3-Hydroxy-2-methylpropionate; Methyl (S)-(+)-3-Hydroxy-2-methylpropionate; Methyl (S)-2-Methyl-3-hydroxypropionate; Methyl (S)-3-Hydroxy-2-methylpropanoate; Methyl (S)-3-Hydroxy-2-methylpropionate; Methyl (S)-3-Hydroxyisobutanoate; Methyl (S)-β-Hydroxyisobutyrate; Methyl 3-Hydroxy-(2S)-methylpropanoate
CAS Number: 80657-57-4
Possible CAS #: NA
Molecular form.: C₅H₁₀O₃
Appearance: Clear Colorless Oil
Melting Point: No Data Available
Mol. Weight: 118.13
Storage: Refrigerator, under inert atmosphere
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Methyl (S)-(+)-3-Hydroxy-2-methylpropionate is an intermediate used to prepare alkoxy- or alkylamino-substituted isoindolinones as inhibitors of the MDM2-p53 protein-protein interaction. It is also used in the synthesis of aliskiren (46, CGP060536B, SPP100), a highly potent, selective inhibitor of renin used for the treatment of hypertension.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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