Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-[N-methyl-N-(methyl-d3-sulfonyl)amino]pyrimidine-5-carboxylate

Catalogue number: M303907
Chemical name: Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-[N-methyl-N-(methyl-d3-sulfonyl)amino]pyrimidine-5-carboxylate
Synonyms: 4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl-d3(methylsulfonyl)amino]-5-pyrimidinecarboxylic Acid Methyl Ester
CAS Number: NA
Possible CAS #: unlabeled: 289042-11-1
Molecular form.: C₁₇H₁₇D₃FN₃O₄S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 384.44
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-[N-methyl-N-(methyl-d3-sulfonyl)amino]pyrimidine-5-carboxylate is an intermediate in the synthesis of Rosuvastatin-d3 Sodium Salt, a labeled analogue of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
Dangerous Goods Info: NA
References: Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005); Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006)
Peer Review Product Citations:

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