2-Methoxy 17β-Estradiol-16,16,17-d3

Catalogue number: M262628
Chemical name: 2-Methoxy 17β-Estradiol-16,16,17-d3
Synonyms: (17β)-2-Methoxy-estra-1,3,5(10)-triene-3,17-diol-16,16,17-d3; 2-Hydroxyestradiol-16,16,17-d3 2-Methyl Ether; 2-Methoxyestra-1,3,5(10)-triene-3,17-diol-16,16,17-d3; NSC 659853-d3;
CAS Number: NA
Possible CAS #: unlabelled: 362-07-2
Molecular form.: C₁₉H₂₃D₃O₃
Appearance: Crystalline Solid
Melting Point: 188-190°C
Mol. Weight: 305.43
Storage: No Data Available
Solubility: Dichloromethane
Stability: No Data Available
Category: Isotope Labelled Compounds, Metabolites & Impurities, Steroids,
Boiling Point: No Data Available
Applications: A natural metabolite of 17β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function.
Dangerous Goods Info: NA
References: Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995), D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1994), Forsis, T., et al.: Nature, 368, 237 (1994)
Peer Review Product Citations:

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