L-Menthyl 2,2-Dihydroxyacetate

Catalogue number: M219145
Chemical name: L-Menthyl 2,2-Dihydroxyacetate
Synonyms: 2,2-Dihydroxyacetic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester; Dihydroxyacetic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester; [1R-(1α,2β,5α)]-Dihydroxyacetic Acid 5-Methyl-2-(1-methylethyl)cyclohexyl Ester; 2,2-Dihydroxyacetic Acid (-)-Menthyl Ester
CAS Number: 111969-64-3
Possible CAS #: NA
Molecular form.: C₁₂H₂₂O₄
Appearance: White Solid
Melting Point: 79-82°C
Mol. Weight: 230.3
Storage: Refrigerator, under inert atmosphere
Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Miscellaneous Reagents
Boiling Point: No Data Available
Applications: L-Menthyl 2,2-Dihydroxyacetate is used as a reagent in the synthesis of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor used for the treatment of chronic hepatitis B. L-Menthyl 2,2-Dihydroxyacetate is also used as a reagent in the synthesis of 4-acetoxy-3-hydroxyethylazetidin-2-one, a key intermediate for the preparation of penem and carbapenem antibiotics.
Dangerous Goods Info: NA
References: Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977); Goodyear, M.D., et al.: Tetrahedron Lett., 46, 8535 (2005); Kametani, T., et al.: Heterocycles, 25, 241 (1987)
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
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