MDV 3100

Catalogue number: M199800
Chemical name: MDV 3100
Synonyms: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide; MDV3100; MDV-3100; Enzalutamide
CAS Number: 915087-33-1
Possible CAS #: NA
Molecular form.: C₂₁H₁₆F₄N₄O₂S
Appearance: White Solid
Melting Point: 198-200°C
Mol. Weight: 464.44
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Apoptosis, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds,
Boiling Point: No Data Available
Applications: MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.
References: Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011);
Dangerous Goods Info: NA

Order Product

  Pack size Price(USD)
5mg $115.00
25mg $360.00
100mg $1250.00
  Pack size Price(USD)
10mg $165.00
50mg $700.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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