MCC-950

Catalogue number: M199775
Chemical name: MCC-950
Synonyms: N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide; CP 456773;
CAS Number: 210826-40-7
Possible CAS #: NA
Molecular form.: C₂₀H₂₄N₂O₅S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 404.48
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: MCC950 selectively inhibits pyrin domain-containing protein 3 (NLRP3) inflammasome, a protein complex involved in the inflammatory process (1). The NLRP3 inflammasome is related to a wide range of immune disorders such as multiple sclerosis, inflammatory bowel disease, auto-immune and auto-inflammatory diseases (2). MCC950 has been shown to specifically inhibit the activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes (1). MCC950 is a potential therapeutic for NLRP3-associated syndromes.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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