MCOPPB Trihydrochloride

Catalogue number: M199500
Chemical name: MCOPPB Trihydrochloride
Synonyms: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride; PF-01678059;
CAS Number: 1108147-88-1
Possible CAS #: freeamine: 1028969-49-4
Molecular form.: C₂₆H₄₃Cl₃N₄
Appearance: White Solid
Melting Point: >249°C (dec.)
Mol. Weight: 518.01
Storage: No Data Available
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: Agonists, Aromatics, Heterocycles, Neurochemicals, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.
Dangerous Goods Info: NA
References: Hayashi, S. et al.: J. Med. Chem., 52, 610 (2009); Hirao, A. et al.: J . Pharmacol. Sci., 106, 361 (2008);
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
1mg $45.00
10mg $145.00
  Pack size Price(USD)
5mg $80.00
100mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Please Inquire

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »