Catalogue number: M110280
Chemical name: Mafodotin
Synonyms: Maleimidocaproyl Monomethylauristatin F; McMMAF; SGD 1269; mc-MMAF; 38: PN: WO2007140371 PAGE: 273 Claimed Protein; N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-Methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine
CAS Number: 863971-19-1
Possible CAS #: NA
Molecular form.: C₄₉H₇₆N₆O₁₁
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 925.16
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amino Acids & Derivatives, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Mafodotin is an anticancer immunoconjugate for the diagnosis and treatment of cancer or B Cell proliferative diseases.
Dangerous Goods Info: NA
References: Valliere-Douglass, J.F., et al.: Anal. Chem., 84, 2843 (2012); Alley, S.C., et al.: Bioconjugate. Chem., 19, 759 (2008); Doronina, S.O., et al.: Bioconjugate. Chem., 17, 114 (2006);
Peer Review Product Citations:

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