LY 2811376

Catalogue number: L486360
Chemical name: LY 2811376
Synonyms: (4S)-4-[2,4-Difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-4H-1,3-Thiazin-2-amine;
CAS Number: 1194044-20-6
Possible CAS #: NA
Molecular form.: C₁₅H₁₄F₂N₄S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 320.36
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: LY 281137 is a compound capable of the decrease in β-amyloid peptide (Aβ) associated with the cleavage of amyloid precursor protein (APP) by β-secretase (BACE) and γ-secretase. This decrease is important as its hypothesized that the build up of (Aβ) in the brain is a primary cause of neurodegeneration and Alzheimer’s progression.
Dangerous Goods Info: NA
References: Mikulca, J.. et al: J. Clin. Pharm. Thera., 39, 25 (2014); Lu, Y. et al.: J. Pharm. Exp. Thera., 342, 366 (2012);
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $45.00
5mg $145.00
50mg $775.00
  Pack size Price(USD)
2.5mg $85.00
10mg $235.00
Exact Weight Packaging ($75(USD) / Vial)
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