LSN 2463359

Catalogue number: L473475
Chemical name: LSN 2463359
Synonyms: N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-Pyridinecarboxamide;
CAS Number: 1401031-52-4
Possible CAS #: NA
Molecular form.: C₁₆H₁₅N₃O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 265.31
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: LSN 2463359 is used as a positive and potent allosteric modulator of the mGlu5 receptor. It is highly selective in this, binding solely to mGlu5 and remaining inactive at receptors mGlu1-4 and mGlu8. Promotes wakefulness in vivo and cognitive activity. Improves memory and learning characteristics in mice.
Dangerous Goods Info: NA
References: Gastambide, F. et al.: Neurpharmacol., 64, 240 (2013); Turlington, M. et al.: J. Med. Chem., 57, 5620 (2014);
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $95.00
50mg $625.00
  Pack size Price(USD)
10mg $145.00
100mg $1050.00
Exact Weight Packaging ($75(USD) / Vial)
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