LSN 2463359

Catalogue number: L473475
Chemical name: LSN 2463359
Synonyms: N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-Pyridinecarboxamide;
CAS Number: 1401031-52-4
Possible CAS #: NA
Molecular form.: C₁₆H₁₅N₃O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 265.31
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: LSN 2463359 is used as a positive and potent allosteric modulator of the mGlu5 receptor (1,2). LSN 2463359 is highly selective for mGlu5 and exhibits little to no activity for mGlu1-4, mGlu8 and GABAB receptors. Studies showed that LSN 2463359 promotes wakefulness in vivo and cognitive activity. LSN 2463359 also Improve memory and learning characteristics in mice.
Dangerous Goods Info: NA
References: PMID: 22884612
PMID: 24914612
Peer Review Product Citations:

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