Lomeguatrib

Catalogue number: L469700
Chemical name: Lomeguatrib
Synonyms: 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine; 6-[(4-Bromo-2-thienyl)methoxy] -1H-purin-2-amine; 2-Amino-6-(4-bromothiophen-2-ylmethoxy)-9H-purine; PaTrin 2;
CAS Number: 192441-08-0
Possible CAS #: NA
Molecular form.: C₁₀H₈BrN₅OS
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 326.17
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: Lomeguatrib is an inhibitor of O6-methylguanine-DNA methyltransferase (MGMT). Lomeguatrib attenuates MGMT activity in vitro and in vivo. Lomeguatrib enhances the antitumor activity of temozolomide in both human melanoma and MCF-7 xenografts.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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