trans-Loperamide N-Oxide

Catalogue number: L469460
Chemical name: trans-Loperamide N-Oxide
Synonyms: trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-Oxide; Arestal; Loperamide Oxide; R 58425
CAS Number: 106900-12-3
Possible CAS #: NA
Molecular form.: C₂₉H₃₃ClN₂O₃
Appearance: Off-White Solid
Melting Point: 169-173°C
Mol. Weight: 493.04
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Drug Analogues, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References:
Peer Review Product Citations:

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