Lonafarnib-d9

Catalogue number: L469447
Chemical name: Lonafarnib-d9
Synonyms: 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide-d9; Sarasar-d9; Sch 66336-d9;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₇H₂₂D₉Br₂ClN₄O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 647.88
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Lonafarnib-d9 is the isotope laballed analog of Lonafarnib. Lonafarnib is an orally bioavailable tricyclic inhibitor of farnesyl protein transferase. It inhibits Rheb farnesylation and mTOR signaling and enhances taxane and tamoxifen antitumor activity. Studies show that it induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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.5mg $275.00
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