Catalogue number: L469445
Chemical name: Lonafarnib
Synonyms: 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide; Sarasar; Sch 66336;
CAS Number: 193275-84-2
Possible CAS #: NA
Molecular form.: C₂₇H₃₁Br₂ClN₄O₂
Appearance: White Solid
Melting Point: 150-152°C
Mol. Weight: 638.82
Storage: Refrigerator
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: An orally bioavailable tricyclic inhibitor of farnesyl protein transferase. It inhibits Rheb farnesylation and mTOR signaling and enhances taxane and tamoxifen antitumor activity. Studies show that it induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells
Dangerous Goods Info: NA
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $50.00
10mg $205.00
50mg $775.00
  Pack size Price(USD)
5mg $105.00
25mg $410.00
100mg $1475.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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