LM 22A4

Catalogue number: L469290
Chemical name: LM 22A4
Synonyms: N1,N3,N5-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide; N,N’,N’’-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide; N,N’,N’’-Tris(β-hydroxyethyl)trimesamide;
CAS Number: 37988-18-4
Possible CAS #: NA
Molecular form.: C₁₅H₂₁N₃O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 339.34
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Agonist, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: LM 22A4 is a potent tropomyosin-related kinase B (TrkB) agonist. LM 22A4 has been show to induce activation of Trk, Akt and ERK in mouse hippocampus and striatum and reverse deficits in motor task learning in mice following traumatic brain injury. LM 22A4 also restored respiratory function in a rat model of Rett syndrome.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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