Catalogue number: L469020
Chemical name: Linsitinib
Synonyms: cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI 906; OSI 906AA;
CAS Number: 867160-71-2
Possible CAS #: NA
Molecular form.: C₂₆H₂₃N₅O
Appearance: Pale Yellow Solid
Melting Point: >175°C (dec.)
Mol. Weight: 421.49
Storage: Refrigerator
Solubility: DMSO
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Boiling Point: No Data Available
Applications: Linsitinib is a small-molecule dual insulin-like growth factor-1 receptor (IGF-IR) and insulin receptor (IR) kinase inhibitor. IGF-I receptor (IGF-IR) has been implicated in the promotion of tumorigenesis, metastasis and resistance to cancer therapies and thus Linsitinib may be a useful anticancer agent.
Dangerous Goods Info: NA
References: Mulvihill, M.M.J. et al.: Fut. Med. Chem., 1, 1153 (2009); Flanigan, S.A. et al.: Clin. Cancer Res., 16, 5436 (2010); McKinley, E.T. et al.: Clin. Cancer Res., 17, 3332 (2011);
Peer Review Product Citations:

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  Pack size Price(USD)
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50mg $575.00
  Pack size Price(USD)
10mg $235.00
100mg $995.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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