LLY-507

Catalogue number: L468905
Chemical name: LLY-507
Synonyms: 5-Cyano-2’-(4-(2-(3-methyl-1H-indol-1-yl)ethyl)piperazin-1-yl)-N-(3-(pyrrolidin-1- yl)propyl)-[1,1’-biphenyl]-3-carboxamide;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₃₆H₄₂N₆O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 574.76
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: LLY-507 is a small molecule inhibitor of SMYD2 (lysine N-methyltransferase), preventing p53 lysine methylation in squamous cell carcinoma cells. Shows a >100-fold selective for SMYD2 over 27 other protein methyltransferases (and non-methyltransferase) targets.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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