Catalogue number: L465882
Chemical name: Linaclotide-d4
Synonyms: L-Cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-d4-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-tyrosine Cyclic (1→6),(2→10),(5→13)-Tris(disulfide); 11: PN: WO2008151257 SEQID: 55 claimed protein-d4; 13: PN: WO2008151257 SEQID: 57 Claimed Protein-d4; 2074: PN: US20090062207 SEQID: 3 Claimed Protein-d4; 40: PN: WO2010065751 SEQID: 55 Claimed Protein-d4; 42: PN: WO2010065751 SEQID: 57 claimed protein-d4; 55: PN: US20100152118 SEQID: 55 Claimed Protein-d4; 55: PN: WO2011069038 SEQID: 55 Claimed Sequence-d4; 55: PN: WO2012037380 SEQID: 55 Unclaimed Protein-d4; 57: PN: WO2011069038 SEQID: 57 Claimed Sequence-d4; 57: PN: WO2012037380 SEQID: 57 Claimed Protein-d4
CAS Number: NA
Possible CAS #: unlabeled: 851199-59-2
Molecular form.: C₅₉H₇₅D₄N₁₅O₂₁S₆
Appearance: White to Off-White Solid
Melting Point: >222°C (dec.)
Mol. Weight: 1530.76
Storage: Refrigerator
Solubility: DMSO (Slightly), Water (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: Linaclotide-d4 is the labeled analogue of a guanylate cyclase-C agonist currently being studied in Phase 3 trials for the treatment of irritable bowel syndrome with constipation.
Dangerous Goods Info: NA
References: Chey, W.D., et al.: Am. J. Gastroenterol., 107, 1702 (2012); Rao, S., et al.: Am. J. Gastroentrol., 107, 1714 (2012); Brierley, S.M., et al.: Curr. Opinion. Pharmacol., 12, 632 (2012);
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
.5mg $300.00
  Pack size Price(USD)
5mg $2400.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »