LB 42708

Catalogue number: L178790
Chemical name: LB 42708
Synonyms: 4-[[1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]carbonyl]morpholine; [1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]-4-morpholinylmethanone; (1-((1-(4-Bromobenzyl)-1H-imidazol-5-yl)methyl)-4-(naphthalen-1-yl)-1H-pyrrol-3-yl)(morpholino)methanone
CAS Number: 226929-39-1
Possible CAS #: NA
Molecular form.: C₃₀H₂₇BrN₄O₂
Appearance: Off-White Solid
Melting Point: No Data Available
Mol. Weight: 555.46
Storage: No Data Available
Solubility: DMSO (Slightly)
Stability: No Data Available
Category: Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: LB 42708 is a selective nonpeptidic Farnesyltransferase (FTase) inhibitor.LB42708 suppresses tumor growth and tumor angiogenesis in both xenograft tumor models of Ras-mutated HCT116 cells and its wild-type Caco-2 cells, indicating its potential application in the treatment of both Ras-mutated and wild type tumors.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
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10mg $145.00
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5mg $80.00
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50mg $650.00
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Exact Weight Packaging ($75(USD) / Vial)
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