Catalogue number: L178525
Chemical name: (S)-Laudanosine
Synonyms: (1S)-1-[(3,4-Dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinoline; Laudanosine; (+)-Laudanosine; (S)-(+)-Laudanosine; (S)-Laudanosine; L-(+)-Laudanosine; L-Laudanosine; (+)-Laudanosine, ; NSC 35045; O-Methylcodamine;
CAS Number: 2688-77-9
Possible CAS #: NA
Molecular form.: C₂₁H₂₇NO₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 357.44
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Laudanosine is a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
References: Canfell, P., et al.: Drug Metab. Dispos., 14, 703 (1986), Anselmi, E., et al.: J. Pharm. Pharmacol., 44, 337 (1992), Bohrer, H., et al.: Pharmacol. Toxicol., 73, 137 (1993),
Dangerous Goods Info: NA

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