Catalogue number: L178520
Chemical name: (R)-Laudanosine
Synonyms: (1R)-1-[(3,4-Dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinoline; (R)-1-[(3,4-Dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinoline; 1βH-Laudanosine; (-)-Laudanosine; D-(-)-Laudanosine; D-Laudanosine; O-Methyllaudanidine; R-(-)-Laudanosine; l-N-Methyltetrahydropapaverine
CAS Number: 85-63-2
Possible CAS #: NA
Molecular form.: C₂₁H₂₇NO₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 357.44
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (R)-Laudanosine is an isomer of (S)-Laudanosine (L178525), a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
Dangerous Goods Info: NA
References: Canfell, P., et al.: Drug Metab. Dispos., 14, 703 (1986); Anselmi, E., et al.: J. Pharm. Pharmacol., 44, 337 (1992); Bohrer, H., et al.: Pharmacol. Toxicol., 73, 137 (1993)
Peer Review Product Citations:

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