KL001

Catalogue number: K571200
Chemical name: KL001
Synonyms: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide
CAS Number: 309928-48-1
Possible CAS #: NA
Molecular form.: C₂₁H₂₂N₂O₄S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 398.48
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: KL001 is a small molecule that specifically interacts with cryptochrome (CRY). KL001 prevented ubiquitin-dependent degrdation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes making it a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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10mg $75.00
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50mg $295.00
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