(-)-α-Kainic Acid Monohydrate

Catalogue number: K445000
Chemical name: (-)-α-Kainic Acid Monohydrate
Synonyms: (2S,3S,4S)-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid Hydrate; [2S-(2α,3β,4β)]-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid Monohydrate
CAS Number: 58002-62-3
Possible CAS #: NA
Molecular form.: C₁₀H₁₇NO₅
Appearance: White Solid
Melting Point: >211°C (dec.)
Mol. Weight: 231.25
Storage: No Data Available
Solubility: Water
Stability: No Data Available
Category: Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (-)-α-Kainic Acid Monohydrate is the monohydrated form of (-)-α-Kainic Acid (K135010); a naturally occurring neuroexcitatory chemical that is a selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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