3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine

Catalogue number: K171000
Chemical name: 3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine
Synonyms: KAAD-Cyclopamine; 11-Deoxyjervine
CAS Number: 306387-90-6
Possible CAS #: NA
Molecular form.: C₄₄H₆₃N₃O₄
Appearance: Pale Yellow Solid
Melting Point: 112-118°C
Mol. Weight: 697.99
Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids,
Boiling Point: No Data Available
Applications: Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ß-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity. KAAD-Cyclopamine compound is unstable in solution.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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.25mg $250.00
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1mg $800.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   Pending QC

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