KD 025

Catalogue number: K145600
Chemical name: KD 025
Synonyms: 2-[3-[4-(1H-Indazol-5-ylamino)-2-quinazolinyl]phenoxy-N-(1-methylethyl)-acetamide;
CAS Number: 911417-87-3
Possible CAS #: NA
Molecular form.: C₂₆H₂₄N₆O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 452.51
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: KD 025 is an inhibitor of Rho-associated protein kinase II (ROCK-II), a serine/threonine kinase that regulates the formation of actin stress fibers and focal adhesions, smooth muscle contraction, and gene expression (1, 2). KD025 has been shown to reduce infarct volume after transient middle cerebral artery occlusion (2).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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