(-)-α-Kainic Acid

Catalogue number: K135010
Chemical name: (-)-α-Kainic Acid
Synonyms: (2S,3S,4S)-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid; 2-Carboxy-4-isopropenyl-3-pyrrolidineacetic Acid; (-)-Kainic Acid; (2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic Acid; Digenic Acid; Digenin; Helminal; Kainic Acid; L-α-Kainic Acid; α-Kainic Acid
CAS Number: 487-79-6
Possible CAS #: NA
Molecular form.: C₁₀H₁₅NO₄
Appearance: White to Off-White Solid
Melting Point: >211°C (dec.)
Mol. Weight: 213.23
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Water (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Inhibitors, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (-)-α-Kainic Acid is a naturally occurring neuroexcitatory chemical that is an selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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