Catalogue number: J211310
Chemical name: JNJ-7706621
Synonyms: N3-[4-(Aminosulfonyl)phenyl]-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazole-3,5-diamine; 4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-yl]amino]benzenesulfonamide; JNJ 770662;
CAS Number: 443797-96-4
Possible CAS #: NA
Molecular form.: C₁₅H₁₂F₂N₆O₃S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 394.36
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: JNJ-770662 is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. JNJ-770662 has been shown to induce growth suppression and mitotic defects, these results suggest that JNJ-7706621 could be useful for cell cycle analysis and therapy of various cancers, including Ewing’s sarcoma.
Dangerous Goods Info: NA
References: Matsuhashi, A. et al.: Curr. Cancer Drug Tar., 12, 625 (2012); Emanue,l S. et al.: Cancer Res., 65, 9038 (2005); Seamon, J.A. et al.: Mol. Cancer Ther., 5, 2459 (2006);
Peer Review Product Citations:

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5mg $175.00
50mg $825.00
Exact Weight Packaging ($75(USD) / Vial)
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