ent-Ivabradine Hydrochloride

Catalogue number: I940505
Chemical name: ent-Ivabradine Hydrochloride
Synonyms: 3-[3-[[[(7R)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; (R)-3-[3-[[(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Monochloride; Bicyclo[4.2.0]octane, 2H-3-benzazepin-2-one deriv.
CAS Number: 148849-68-7
Possible CAS #: Free base: 167072-91-5
Molecular form.: C₂₇H₃₇ClN₂O₅
Appearance: White Solid
Melting Point: >125°C (dec.)
Mol. Weight: 505.05
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: ent-Ivabradine Hydrochloride is the enantiomer of Ivabradine Hydrochloride (I940500); a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also an antianginal.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994); Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998); Borer, J.S., et al.: Circulation, 107, 817 (2003); DiFrancesco, D., et al.: Drugs, 64, 1757 (2004)
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $150.00
  Pack size Price(USD)
10mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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