Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt

Catalogue number: I824640
Chemical name: Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt
Synonyms: N-(Hydroxyphenoxyphosphinyl)-L-alanine 1-Methylethyl Ester Sodium Salt; (2S)-Isopropyl 2-((Hydroxy(phenoxy)phosphoryl)amino)propanoate Sodium Salt
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₁₂H₁₇NNaO₅P
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 309.23
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Amines, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt is an impurity of Sofosbuvir (P839640), a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-α-fluoro-β-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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