Isoniazid-d4

Catalogue number: I821452
Chemical name: Isoniazid-d4
Synonyms: 4-(Pyridine-d4)carboxylic Acid Hydrazide; Isonicotinic Acid-d4 Hydrazide; 4-(Hydrazinocarbonyl)pyridine-d4; 4-(Pyridine-d4)carbonylhydrazine; 4-(Pyridine-d4)carboxylic Hydrazide; 4-(Pyridyl-d4)carbonylhydrazide; 5015 R.P.-d4; Armazid-d4; Armazide-d4; Atcotibine-d4; Isonizide-d4; Isotebezid-d4; Isozide-d4; Robisellin-d4; Sauterazid-d4; Zinadon-d4; Zonazide-d4; Tubazid-d4;
CAS Number: 774596-24-6
Possible CAS #: NA
Molecular form.: C₆H₃D₄N₃O
Appearance: White to Off-White Solid
Melting Point: 159-1610C
Mol. Weight: 141.16
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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