(4-Isobutylphenyl)plumbanetriyl Triacetate

Catalogue number: I780350
Chemical name: (4-Isobutylphenyl)plumbanetriyl Triacetate
Synonyms: Tris(acetyloxy)[4-(2-methylpropyl)phenyl]-plumbane
CAS Number: 74610-74-5
Possible CAS #: NA
Molecular form.: C₁₆H₂₂O₆Pb
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 517.54
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (4-Isobutylphenyl)plumbanetriyl Triacetate is an intermediate in the synthesis of Ibuprofen-d3 (I140002), a labelled Ibuprofen, a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
Dangerous Goods Info: NA
References: Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)
Peer Review Product Citations:

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