Catalogue number: I728900
Chemical name: 5-Iodouracil
Synonyms: 5-Iodo-2,4(1H,3H)-pyrimidinedione; 5-Iodo-2,4-dihydroxypyrimidine; 5-Iodo-2,4-pyrimidinedione; 5-Iodopyrimidine-2,4-diol; 5-Iodouracil; NSC 57848;
CAS Number: 696-07-1
Possible CAS #: NA
Molecular form.: C₄H₃IN₂O₂
Appearance: Off-White Solid
Melting Point: 266-270°C
Mol. Weight: 237.98
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Heterocycles, Nucleotides, Bases & Related Reagents,
Boiling Point: No Data Available
Applications: 5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.
Dangerous Goods Info: NA
References: Meisenheimer, K. et al.: Meth. Enzymol., 318, 88 (2000); Klecker, R.W. Jr. et al.: Cancer Chemother. Pharmacol., 48, 407 (2001); Turner, D.P. et al.: Cancer Res., 66, 7686 (2006);
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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